L-HPC®
Shin-Etsu
L-HPC is used as a binder and a disintegrant for solid dosage forms. It was brought onto the market in 1977, and then listed in the JP in 1986, in the NF in 1990 and in the EP in 2016. This product exhibits a wide range of compatibility with many active substances. It is a suitable binder and disintegrant for a formulation study. We have developed a NBD for the L-HPC family. This is chemically identical to the current L-HPC grades, but the particle shape is physically designed to significantly improve binding capability. Low-substituted hydroxypropyl cellulose