Experts in Excipients

MEGGLE

MEGGLE Excipients produces high-quality pharmaceutical excipients tailored for various formulations, including direct compression, granulation, capsules, sachets, powder blends, and dry powder inhalation. MEGGLE has established a prominent position within the global excipient market by leveraging a comprehensive product portfolio and innovative solutions. With production facilities in Wasserburg am Inn, Germany and Le Sueur, Minnesota, MEGGLE serves the requirements of the North American market, and it is prepared to meet customer expectations

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Product Portfolio

MEGGLE

Discover MEGGLE’s incredible product portfolio, with diverse options designed to meet every need! Dive into the world of MEGGLE and unlock the perfect match for your requirements!

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Sieved lactose – with superior blending properties.


Lactose is sieve-fractionated into various grades with narrow particle size distributions and exhibits good flow. Sieved lactose consists of mono-crystals and agglomerates. The variety of products allows you to optimize your selection for your particular application. Good blending properties and excellent flowability make these products especially well-suited to powder blends, and capsule and sachet filling.

 

Applications:

Capsule filling

Sachet filling

Powder blend

Triturations

 

Advantages:

Excellent flowability

Narrow particle size distribution

Good blending properties

High storage stability

High batch-to-batch consistency

Milled lactose – for optimum granulation.


Milled Lactose shows a limited flowability and should therefore be granulated before tabletting. GranuLac® and SorboLac® have a small particle size. Because of its good compression and blending properties, lactose is the most frequently used excipient for granulation.

Applications:  

Wet granulation

Dry compression

Premixes

Triturations

Fermentation

Flavor off-set

 

Advantages:

Good compactibility

Good blending properties

Narrow particle size distribution

High storage stability

High batch-to-batch consistency

Maximum profitability

Direct Compression (DC)

Direct compression is the alternative to traditional granulation. Because they are convenient and safe to administer, tablets are the most popular pharmaceutical dosage form. They can be produced inexpensively in large volumes. Moreover, the prescribed active ingredient dosage can be prepared with a higher degree of accuracy. In the pharmaceutical industry, Direct Compression has already become the preferred method for manufacturing tablets. This is because of its economical production due to cost-effectiveness in manufacturing sites, labor, validation, as well as the increase in overall stability of the active ingredient within the tablet.
The selection of pharmaceutical excipients for direct compression is more critical than that for granulation in general, or wet granulation. Few traditional excipients combine the functional characteristics, specifically powder flow and compactibility, required for robust direct compression. This makes modifying traditional excipients a necessity

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flexible, according to your requirements

Lactose for inhalation applications

InhaLac® is sieved, milled or micronized pharmaceutical lactose that is especially suited to applications in dry powder inhalation drug delivery. The InhaLac® product line is available in standard formulation or as a customized solutions to suit your requirements. Sieved InhaLac® has excellent flowability, defined particle surface, and chemical and physical stability that are the characteristics needed in dry powder inhalation excipients. The sieved product qualities are practically free of amorphous lactose.
The finely milled lactose InhaLac® 400 as well as the micronized lactose InhaLac® 500 are both excellently suited as tertiary components in dry powder inhalation drug delivery. As such, they are able to elevate the efficiency of the formulation. In addition they may serve as the basis for soft pellet formulations. InhaLac®’s special suitabilities are due to its narrow particle size distribution.

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